Tottenham and West Ham will renew their rivalry with both teams fighting for a Champions League spot.
Both teams come into this one on good form with Spurs seeing off Brighton Hove and Albion while West Ham put up a splendid show to beat Sevilla 2-1 to progress in the Europa League.
Added to the fact that Arsenal won at Villa on Saturday means both sides have little room for error, it’s all set up for an epic encounter.
For Tottenham, qualifying for the Champions League will be a massive success given the troubles of the season and the fact that they had to replace Nuno Espirito Santo with Antonio Conte.
However since arriving in north London, the Italian manager continues to cast doubt over his long term future at the club, and has consistently highlighted the need for the team to align with his individual ambitions.
The good news is that, he has managed to return key striker Harry Kane to some form and that is always the starting point if Spurs are going to do well.
West Ham’s season continues to gather pace and the Irons will arrive in north London buoyed by the fact they have just become the first English side to knock Sevilla out of the Europa League.
Tottenham manager Antonio Continue admitted David Moyes’ team were a tough team to play against but was confident his side has what it takes to get the job done.
He Spurs boss added: “It’s a derby and don’t forget that a derby is always difficult, but I think that my team, we are now in a good moment of form. We are improving a lot. We try to do everything to get three points.
“It’s difficult to play West Ham because it’s difficult to find their players out of position and also when they attack, they’re very prepared, they’re good defensively. You have to pay great attention because they’re also very strong on set pieces.”
So how will the Lillywhites line-up, below we predict the team.