Mikel Arteta’s side were unfortunate to not get all three points from their 1-1 draw against Brentford on Saturday.
An error from the VAR at Stockley Park saw Ivan Toney’s goal stand when it should have been ruled out due to Christian Norgaard being in an offside position.
Arsenal were understandably furious at the time but those feelings have quickly wavered into focus and concentration ahead of arguably the biggest game of the season so far.
Former Manchester City forward Gabriel Jesus is still a few weeks from returning to full fitness, while Emile Smith Row is not yet in contention to be involved.
City boss Pep Guardiola has suggested that Erling Haaland may be doubtful for Wednesday’s game, although it remains to be seen whether or not he’ll be selected for the game at Emirates Stadium.
Here is a look at how Arsenal could choose to line up in their pivotal league encounter:
5. LB - Oleksandr Zinchenko
Likely to start against his former club and will be geared up for this one. | Getty Images
6. CM - Thomas Partey
A certainty to start in midfield. | Getty Images
7. CM - Granit Xhaka
Another player who is one of the first names on the teamsheet. Offers leadership and experience in abundance. | Arsenal FC via Getty Images
8. CM - Martin Odegaard
One of the best creative midfielders in the league this season. Almost guaranteed to start. Photo: Clive Rose