Chelsea manager Mauricio Pochettino has named Malo Gusto at right back and Benoit Badiashile is on the bench for the first time this season.
The French defender's return to the team will provide needed options at the centre of defence and there is also a return for captain Reece James who hasn't played since the Premier League opening draw against Liverpool.
Arsenal have won six of their past seven matches against Chelsea in all competitions, as many victories as in the previous 25 meetings. The visitors are vying to win four consecutive league games versus Chelsea for the first time.
Chelsea have won their last four games coming into this one so it will be interesting to see if the international break halts their momentum or provides for them a springboard to go on and excel this season.
The stakes are high and Arsenal can become the first team to win their opening four away games in a top-flight season without conceding a goal.
So with all that in mind, here is the team manager Mauricio Pochettino has named with pretty much everyone who has been playing this season named in the team.
1. Robert Sanchez
The Spain goalkeeper will hope to continue from where he left off before the break
2. Malo Guto
Malo Gusto gets the nod to start ahead of James and Cucurella
3. Thiago Silva
The main man with all the experience at the back.
4. Moises Caicedo
Has been playing well in the last few weeks.