Great Ormond Street Hospital for Children Trust was caring for four patients with coronavirus in hospital as of Wednesday, figures show.
NHS England data shows the number of people being treated in hospital with Covid-19 by 8am on March 15 was down from five on the same day the previous week.
There were two beds occupied by patients with Covid-19 four weeks ago in Great Ormond Street Hospital for Children NHS Foundation Trust.
Across England there were 8,434 people in hospital with Covid as of March 15, with 184 of them in mechanical ventilation beds.
Nationally, the number of hospital patients with Covid-19 has increased by 17% in the last four weeks, while the number on mechanical ventilators has increased by 34%.
The figures also show that one new patient with Covid was admitted to hospital in Great Ormond Street Hospital for Children NHS Foundation Trust in the week to March 13. This was down from five in the previous seven days.