Spurs are going into the game knowing that anything but a win will deflate their Champions League ambitions, with Arsenal expected to beat Leeds on Sunday.
For Liverpool, they know any slip will likely end their Premier League title challenge, with leaders Manchester City having the easier run in.
The best Jurgen Klopp’s men can do is to continue tightening the pressure valve on their North West rivals.
Spurs returned to winning ways over the weekend after a 3-1 victory over Leicester, their first win three following a defeat to Brighton and a disappointing draw to Brentford.
Forward Steven Bergwijn revealed the win was the best preparation ahead of Liverpool, and that Tottenham need to be ready physically and tactically to cause havoc to their in-form opponents.
The Spurs forward told LondonWorld: “After the draw and the defeat against Brighton, it was important to get back to winning.
“I think here we played a good game against them [Liverpool], so I think if we play better and improve physically and more tactically then we have a good chance.
“We also have world class players and we are very confident in the group we have here.”
The two sides played out a 2-2 draw at the Tottenham Hotspur Stadium, with the hosts having several gilt-edged chances to win the game.
And the Dutch forward admitted that eyes are already on the north London derby next week.
He added: “Of course we watch Arsenal, but we have to focus on ourselves and that means if we win the last four games then we have Champions League football, so that is where the main focus is at the moment.”
Spurs are fifth in the league table on 61 points, two behind Arsenal in fourth, while Liverpool are second on 82 points, just one behind Manchester City.